Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections

Polymyxin B (PMB), a kind of polymyxin, was widely used in carbapenem-resistant Gram-negative bacterial (CR-GNB) infections. However, adverse reactions such as nephrotoxicity and neurotoxicity limit its use in clinical practice. The aim of this study was to explore PMB associated with nephrotoxicity...

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Main Authors: Xiao-Li Wu, Wen-Ming Long, Qiong Lu, Xin-Qi Teng, Ting-Ting Qi, Qiang Qu, Ge-Fei He, Jian Qu
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2022-04-01
叢編:Frontiers in Pharmacology
主題:
polymyxin B
nephrotoxicity
acute kidney injury
carbapenem-resistant Gram-negative bacteria
adverse reactions
在線閱讀:https://www.frontiersin.org/articles/10.3389/fphar.2022.672543/full
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