Polymyxin B-Associated Nephrotoxicity and Its Predictors: A Retrospective Study in Carbapenem-Resistant Gram-Negative Bacterial Infections

Polymyxin B (PMB), a kind of polymyxin, was widely used in carbapenem-resistant Gram-negative bacterial (CR-GNB) infections. However, adverse reactions such as nephrotoxicity and neurotoxicity limit its use in clinical practice. The aim of this study was to explore PMB associated with nephrotoxicity...

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Hauptverfasser: Xiao-Li Wu, Wen-Ming Long, Qiong Lu, Xin-Qi Teng, Ting-Ting Qi, Qiang Qu, Ge-Fei He, Jian Qu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-04-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
polymyxin B
nephrotoxicity
acute kidney injury
carbapenem-resistant Gram-negative bacteria
adverse reactions
Online Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2022.672543/full
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