Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

Abstract Background Corticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment. However, it is not known if or when corticosteroids can...

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Detaylı Bibliyografya
Asıl Yazarlar: Amber J. Giles, Marsha-Kay N. D. Hutchinson, Heather M. Sonnemann, Jinkyu Jung, Peter E. Fecci, Nivedita M. Ratnam, Wei Zhang, Hua Song, Rolanda Bailey, Dionne Davis, Caitlin M. Reid, Deric M. Park, Mark R. Gilbert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2018-06-01
Seri Bilgileri:Journal for ImmunoTherapy of Cancer
Konular:
Corticosteroids
Immunotherapy
Glioma
Checkpoint blockade
Dexamethasone
Online Erişim:http://link.springer.com/article/10.1186/s40425-018-0371-5
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