Efficient Synthesis of Kinsenoside and Goodyeroside A by a Chemo-Enzymatic Approach

Kinsenoside (1) and goodyeroside A (2), two naturally occurring stereoisomers with diverse biological activities, have been synthesized efficiently by a chemo-enzymatic approach with a total yield of 12.7%. The aglycones, (R)- and (S)-3-hydroxy-γ-butyrolactone, were prepared from D- and L-malic acid...

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Bibliographic Details
Main Authors: Yang Zhang, Yihong Xia, Yongji Lai, Fang Tang, Zengwei Luo, Yongbo Xue, Guangmin Yao, Yonghui Zhang, Jinwen Zhang
Format: Artigo
Language:Inglês
Published: MDPI AG 2014-10-01
Series:Molecules
Subjects:
kinsenoside
goodyeroside A
chemo-enzymatic synthesis
glucosidase
biocatalysis
Online Access:http://www.mdpi.com/1420-3049/19/10/16950
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