GSK-3β-Targeting Fisetin Promotes Melanogenesis in B16F10 Melanoma Cells and Zebrafish Larvae through β-Catenin Activation

Fisetin is found in many fruits and plants such as grapes and onions, and exerts anti-inflammatory, anti-proliferative, and anticancer activity. However, whether fisetin regulates melanogenesis has been rarely studied. Therefore, we evaluated the effects of fisetin on melanogenesis in B16F10 melanom...

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Auteurs principaux: Ilandarage Menu Neelaka Molagoda, Wisurumuni Arachchilage Hasitha Maduranga Karunarathne, Sang Rul Park, Yung Hyun Choi, Eui Kyun Park, Cheng-Yun Jin, Haiyang Yu, Wol Soon Jo, Kyoung Tae Lee, Gi-Young Kim
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2020-01-01
Collection:International Journal of Molecular Sciences
Sujets:
fisetin
melanogenesis
α-msh
gsk-3β
β-catenin
Accès en ligne:https://www.mdpi.com/1422-0067/21/1/312
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