SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK

Obesity is increasing at an alarming rate worldwide, which is characterized by the excessive accumulation of triglycerides in adipocytes. Emerging evidence has demonstrated that macroautophagy and chaperone-mediated autophagy (CMA) regulate lipid mobilization and play a key role in energy balance. S...

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Bibliographic Details
Main Authors: Tian Zhang, Jingxin Liu, Qiang Tong, Ligen Lin
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
sirtuin 3
lipid metabolism
macroautophagy
chaperone-mediated autophagy
ampk
Online Access:https://www.mdpi.com/1422-0067/21/2/372
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