SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK

Obesity is increasing at an alarming rate worldwide, which is characterized by the excessive accumulation of triglycerides in adipocytes. Emerging evidence has demonstrated that macroautophagy and chaperone-mediated autophagy (CMA) regulate lipid mobilization and play a key role in energy balance. S...

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Main Authors: Tian Zhang, Jingxin Liu, Qiang Tong, Ligen Lin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Assuntos:
sirtuin 3
lipid metabolism
macroautophagy
chaperone-mediated autophagy
ampk
Acceso en liña:https://www.mdpi.com/1422-0067/21/2/372
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