Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33

Medulloblastoma is the most common malignant tumor that arises from the cerebellum of the central nervous system. Clinically, medulloblastomas are treated by surgery, radiation, and chemotherapy, all of which result in toxicity and morbidity. Recent reports have identified that DDX3, a member of the...

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Hlavní autoři: Saritha Tantravedi, Farhad Vesuna, Paul T. Winnard, Jr., Allison Martin, Michael Lim, Charles G. Eberhart, Cynthia Berlinicke, Eric Raabe, Paul J. van Diest, Venu Raman
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019-01-01
Edice:Translational Oncology
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1936523318303097
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