The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b

The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major endothelial junctional proteins. We focus on miR-23a a...

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Hauptverfasser: Jia Li, Yang Zhao, Ying Lu, William Ritchie, Georges Grau, Mathew A Vadas, Jennifer R Gamble
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016-01-01
Schriftenreihe:Molecular Therapy: Nucleic Acids
Schlagworte:
miR-23-27-24
endothelial cells
cell-cell junctions
miR-23
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2162253117300768
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