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Biophysical and functional study of CRL5Ozz, a muscle specific ubiquitin ligase complex
Abstract Ozz, a member of the SOCS-box family of proteins, is the substrate-binding component of CRL5Ozz, a muscle-specific Cullin-RING ubiquitin ligase complex composed of Elongin B/C, Cullin 5 and Rbx1. CRL5Ozz targets for proteasomal degradation selected pools of substrates, including sarcolemma-...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Nature Portfolio
2022-05-01
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Series: | Scientific Reports |
Acceso en liña: | https://doi.org/10.1038/s41598-022-10955-w |
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