Direct Implementation of Intestinal Permeability Test in NMR Metabolomics for Simultaneous Biomarker Discovery—A Feasibility Study in a Preterm Piglet Model

Measurement of intestinal permeability (IP) is often used in the examination of inflammatory gastrointestinal disorders. IP can be assessed by measurement of urinary recovery of ingested non-metabolizable lactulose (L) and mannitol (M). The present study aimed to examine how measurements of IP can b...

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Autores principales: Masoumeh Alinaghi, Duc Ninh Nguyen, Per Torp Sangild, Hanne Christine Bertram
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2020-01-01
Colección:Metabolites
Materias:
intestinal barrier dysfunction
leaky gut
preterm infants
lipopolysaccharide (lps)
prenatal inflammation
nmr metabolomics
lactulose
Acceso en línea:https://www.mdpi.com/2218-1989/10/1/22
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