Virtual Screening of Specific Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors from the National Cancer Institute (NCI) Molecular Database

Insulin-like growth factor 1 receptor (IGF1R) is an attractive drug target for cancer therapy and research on IGF1R inhibitors has had success in clinical trials. A particular challenge in the development of specific IGF1R inhibitors is interference from insulin receptor (IR), which has a nearly ide...

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Détails bibliographiques
Auteurs principaux: Yu-Xin Li, Li-Hua Zheng, Guan-Nan Wang, Ying Sun, Zhen-Bo Song, Yu Zhang, Chun-Lei Yu, Yong-Li Bao, Yin Wu, Lu-Guo Sun, Yan-Xin Huang, Cong Fan
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2012-12-01
Collection:International Journal of Molecular Sciences
Sujets:
IGF1R
IR
virtual screening
binding mode prediction
selective inhibition
Accès en ligne:http://www.mdpi.com/1422-0067/13/12/17185
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