Virtual Screening of Specific Insulin-Like Growth Factor 1 Receptor (IGF1R) Inhibitors from the National Cancer Institute (NCI) Molecular Database

Insulin-like growth factor 1 receptor (IGF1R) is an attractive drug target for cancer therapy and research on IGF1R inhibitors has had success in clinical trials. A particular challenge in the development of specific IGF1R inhibitors is interference from insulin receptor (IR), which has a nearly ide...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu-Xin Li, Li-Hua Zheng, Guan-Nan Wang, Ying Sun, Zhen-Bo Song, Yu Zhang, Chun-Lei Yu, Yong-Li Bao, Yin Wu, Lu-Guo Sun, Yan-Xin Huang, Cong Fan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2012-12-01
Cyfres:International Journal of Molecular Sciences
Pynciau:
IGF1R
IR
virtual screening
binding mode prediction
selective inhibition
Mynediad Ar-lein:http://www.mdpi.com/1422-0067/13/12/17185
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

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