Cytotoxicity and Antioxidant Potential of Novel 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole Derivatives

Newly synthesized 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole derivatives were evaluated for their in vitro cytotoxicity on two carcinoma cell lines A2780 and HeLa. Significant cytotoxic activity for 2-(2-((1H-indol-5-yl)methylene)hydrazinyl)-4-methylthiazole (1) and 2-(2-((1H-indol-5-yl)met...

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Autori principali: Adriana Grozav, Ioan-Dan Porumb, Luiza Ioana Găină, Lorena Filip, Daniela Hanganu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2017-02-01
Serie:Molecules
Soggetti:
cytotoxic activity
antioxidant activity
DFT calculation
indol
thiazole
Accesso online:http://www.mdpi.com/1420-3049/22/2/260
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