Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.

Caveolin-1 (CAV-1) participates in regulating vesicular transport, signal transduction, tumor progression, and cholesterol homeostasis. In the present study, we tested the hypothesis that CAV-1 improves dyslipidemia, inhibits cyclophilin A (CypA)- mediated ROS production, prevents mitochondrial comp...

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Main Authors: Ya-Hui Chen, Wei-Wen Lin, Chin-San Liu, Li-Sung Hsu, Yueh-Min Lin, Shih-Li Su
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4849769?pdf=render
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