The Pictet-Spengler Reaction Updates Its Habits

The Pictet-Spengler reaction (P-S) is one of the most direct, efficient, and variable synthetic method for the construction of privileged pharmacophores such as tetrahydro-isoquinolines (THIQs), tetrahydro-&#946;-carbolines (THBCs), and polyheterocyclic frameworks. In the <i>lustro</i&g...

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Bibliographic Details
Main Authors: Andrea Calcaterra, Laura Mangiardi, Giuliano Delle Monache, Deborah Quaglio, Silvia Balducci, Simone Berardozzi, Antonia Iazzetti, Roberta Franzini, Bruno Botta, Francesca Ghirga
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
pictet-spengler
tetrahydroisoquinoline
thiq
tetrahydro-β-carboline
thbc
alkaloid
total synthesis
natural products
cascade reaction
multicomponent reaction
Online Access:https://www.mdpi.com/1420-3049/25/2/414
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