Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy

Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types. The nAChRs expressed in mitochondria regulate the rel...

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Main Authors: Kateryna Uspenska, Olena Lykhmus, Maria Obolenskaya, Stephanie Pons, Uwe Maskos, Serhiy Komisarenko, Maryna Skok
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-06-01
Serija:Frontiers in Pharmacology
Teme:
nicotinic acetylcholine receptor
mitochondria
knockout mice
partial hepatectomy
cytochrome c
mitochondrial kinases
Online dostop:https://www.frontiersin.org/article/10.3389/fphar.2018.00626/full
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