Multivariate genome-wide association analysis identifies novel and relevant variants associated with anterior cruciate ligament rupture risk in the dog model

Abstract Background Anterior cruciate ligament rupture (ACLR) is a debilitating and potentially life-changing condition in humans, as there is a high prevalence of early-onset osteoarthritis after injury. Identification of high-risk individuals before they become patients is important, as post-treat...

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Hlavní autoři: Lauren A. Baker, Guilherme J. M. Rosa, Zhengling Hao, Alexander Piazza, Christopher Hoffman, Emily E. Binversie, Susannah J. Sample, Peter Muir
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-06-01
Edice:BMC Genetics
Témata:
ACL rupture
CCL rupture
GWAS
Complex trait
Canine
Bayesian approach
On-line přístup:http://link.springer.com/article/10.1186/s12863-018-0626-7
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