KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer.

BACKGROUND:KIAA1199 was upregulated in diverse cancers, but the association of KIAA1199 with gastric cancer (GC), the biological role of KIAA1199 in GC cells and the related molecular mechanisms remain to be elucidated. METHODS:KIAA1199 expression was analysed by reverse transcription-polymerase cha...

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Main Authors: Shuqin Jia, Tingting Qu, Xiaohong Wang, Mengmeng Feng, Yang Yang, Xuemin Feng, Ruiting Ma, Wenmei Li, Ying Hu, Yi Feng, Ke Ji, Ziyu Li, Wenguo Jiang, Jiafu Ji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2017-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC5397282?pdf=render
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