An Efficient Evaluation System Accelerates α-Helical Antimicrobial Peptide Discovery and Its Application to Global Human Genome Mining

Antimicrobial peptides (AMPs), as an important part of the innate immune system of an organism, is a kind of promising drug candidate for novel antibiotics due to their unique antibacterial mechanism. However, the discovery of novel AMPs is facing a great challenge due to the complexity of systemati...

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Autori principali: Licheng Liu, Caiyun Wang, Mengyue Zhang, Zixuan Zhang, Yingying Wu, Yixuan Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-04-01
Serie:Frontiers in Microbiology
Soggetti:
antimicrobial peptide
screening system
antimicrobial activity
antimicrobial mechanism
mouse model
skin infection
Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2022.870361/full
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