Characterization of <it>CDKN2A</it>(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing

<p>Abstract</p> <p>Background</p> <p>The aim of this study is to analyse <it>CDKN2A</it> methylation using pyrosequencing on a large cohort of colorectal cancers and corresponding non-neoplastic tissues. In a second step, the effect of methylation on clinica...

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Main Authors: Bihl Michel P, Foerster Anja, Lugli Alessandro, Zlobec Inti
Format: Artigo
Jezik:Inglês
Izdano: BMC 2012-08-01
Serija:Journal of Translational Medicine
Teme:
Colorectal cancer
<it>CDKN2A</it>
p16
Methylation
Pyrosequencing
Online dostop:http://www.translational-medicine.com/content/10/1/173
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