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Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome
Abstract Background Fascin-1, a prominent actin-bundling protein, is found to be upregulated in several human carcinomas. While it is accepted that Fascin-1 expression correlates with poor clinical outcome and decreased survival in various carcinomas, its role in sarcoma such as osteosarcoma (OS) re...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
BMC
2019-01-01
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Schriftenreihe: | BMC Cancer |
Schlagworte: | |
Online Zugang: | http://link.springer.com/article/10.1186/s12885-019-5303-3 |
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