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Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan <i>O-</i>Acetyltransferases, New Potential Antibacterial Targets

The <i>O</i>-acetylation of peptidoglycan occurs in many Gram-negative and most Gram-positive pathogens and this modification to the essential wall polymer controls the lytic activity of the autolysins, particularly the lytic transglycosylases, and inhibits that of the lysozymes of innat...

詳細記述

保存先:
書誌詳細
主要な著者: Ashley S. Brott, Carys S. Jones, Anthony J. Clarke
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2019-05-01
シリーズ:Antibiotics
主題:
HTS
オンライン・アクセス:https://www.mdpi.com/2079-6382/8/2/65
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