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Development of a High Throughput Screen for the Identification of Inhibitors of Peptidoglycan <i>O-</i>Acetyltransferases, New Potential Antibacterial Targets

The <i>O</i>-acetylation of peptidoglycan occurs in many Gram-negative and most Gram-positive pathogens and this modification to the essential wall polymer controls the lytic activity of the autolysins, particularly the lytic transglycosylases, and inhibits that of the lysozymes of innat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ashley S. Brott, Carys S. Jones, Anthony J. Clarke
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2019-05-01
श्रृंखला:Antibiotics
विषय:
HTS
ऑनलाइन पहुंच:https://www.mdpi.com/2079-6382/8/2/65
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