Tissue specific DNA methylation in normal human breast epithelium and in breast cancer.

Cancer is a heterogeneous and tissue-specific disease. Thus, the tissue of origin reflects on the natural history of the disease and dictates the therapeutic approach. It is suggested that tissue differentiation, mediated mostly by epigenetic modifications, could guide tissue-specific susceptibility...

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Bibliografiska uppgifter
Huvudupphovsmän: Ayelet Avraham, Sean Soonweng Cho, Ronit Uhlmann, Mia Leonov Polak, Judith Sandbank, Tami Karni, Itzhak Pappo, Ruvit Halperin, Zvi Vaknin, Avishay Sella, Saraswati Sukumar, Ella Evron
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3961270?pdf=render
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