A genome-wide association study of optic disc parameters.

The optic nerve head is involved in many ophthalmic disorders, including common diseases such as myopia and open-angle glaucoma. Two of the most important parameters are the size of the optic disc area and the vertical cup-disc ratio (VCDR). Both are highly heritable but genetically largely undeterm...

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Autori principali: Wishal D Ramdas, Leonieke M E van Koolwijk, M Kamran Ikram, Nomdo M Jansonius, Paulus T V M de Jong, Arthur A B Bergen, Aaron Isaacs, Najaf Amin, Yurii S Aulchenko, Roger C W Wolfs, Albert Hofman, Fernando Rivadeneira, Ben A Oostra, Andre G Uitterlinden, Pirro Hysi, Christopher J Hammond, Hans G Lemij, Johannes R Vingerling, Caroline C W Klaver, Cornelia M van Duijn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-06-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC2883590?pdf=render
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