An acid-sensing ion channel that detects ischemic pain

Ischemic pain occurs when there is insufficient blood flow for the metabolic needs of an organ. The pain of a heart attack is the prototypical example. Multiple compounds released from ischemic muscle likely contribute to this pain by acting on sensory neurons that innervate muscle. One such compoun...

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Bibliographic Details
Main Authors: L.A. Naves, E.W. McCleskey
Format: Artigo
Language:Inglês
Published: Associação Brasileira de Divulgação Científica 2005-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Pain
Ischemia
Dorsal root ganglia
Acid-sensing ion channels
Lactic acidosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100001
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