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Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2.

Toll like receptors (TLRs) are pattern-recognition molecules that initiate the innate immune response to pathogens. Pulmonary surfactant protein (SP)-A is an endogenously produced ligand for TLR2 and TLR4. SP-A has been proposed as a fetally produced signal for the onset of parturition in the mouse....

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Autors principals: Varkha Agrawal, Keith Smart, Tamas Jilling, Emmet Hirsch
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2013-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3659120?pdf=render
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