Immunophenotyping of Peripheral Blood, Lymph Node, and Bone Marrow T Lymphocytes During Canine Leishmaniosis and the Impact of Antileishmanial Chemotherapy

Dogs are a major reservoir of Leishmania infantum, etiological agent of canine leishmaniosis (CanL) a zoonotic visceral disease of worldwide concern. Therapeutic protocols based on antileishmanial drugs are commonly used to treat sick dogs and improve their clinical condition. To better understand t...

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Main Authors: Marcos Ferreira Santos, Graça Alexandre-Pires, Maria A. Pereira, Lídia Gomes, Armanda V. Rodrigues, Alexandra Basso, Ana Reisinho, José Meireles, Gabriela M. Santos-Gomes, Isabel Pereira da Fonseca
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-07-01
Serier:Frontiers in Veterinary Science
Fag:
antileishmanial therapy
bone marrow
canine leishmaniosis
effector T cells
flow cytometry
lymph node
Online adgang:https://www.frontiersin.org/article/10.3389/fvets.2020.00375/full
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