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The immunodominant T cell epitopes of the mycolyl-transferases of the antigen 85 complex of M. tuberculosis.

The Ag85 complex is a 30-32 kD family of three proteins (Ag85A, Ag85B and Ag85C), which all three possess enzymatic mycolyl-transferase activity involved in the coupling of mycolic acids to the arabinogalactan of the cell wall and in the biogenesis of cord factor. By virtue of their strong potential...

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Autor principal: Kris eHuygen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014-07-01
Colección:Frontiers in Immunology
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Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00321/full
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