Acetylation stabilizes stathmin1 and promotes its activity contributing to gallbladder cancer metastasis

Abstract Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabilization. We identified the acetylation of stahtmi...

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Bibliografiske detaljer
Main Authors: Kun Fan, Xiaojian Ni, Sheng Shen, Zijun Gong, Jiwen Wang, Yanlei Xin, Bohao Zheng, Wentao Sun, Han Liu, Tao Suo, Xiaoling Ni, Houbao Liu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2022-05-01
Serier:Cell Death Discovery
Online adgang:https://doi.org/10.1038/s41420-022-01051-z
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