Downregulation of Immunosuppressive Molecules, PD-1 and PD-L1 but not PD-L2, in the Patients with Multiple Sclerosis

Programmed cell death-1 (PD-1) and its ligands, PD-L1 and PD-L2, have been regarded as important immune system regulatory molecules. The aberrant expression of the molecules has been related to several autoimmune disorders. This study is aimed to assess the mRNA expression level of PD-1, PD-L1, and...

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Hauptverfasser: Mohammad Reza Javan, Saeed Aslani, Mohammad Reza Zamani, Javad Rostamnejad, Milad Asadi, Mahdi Farhoodi, Mohammad Hossein Nicknam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tehran University of Medical Sciences 2016-08-01
Schriftenreihe:Iranian Journal of Allergy, Asthma and Immunology
Schlagworte:
Gene expression
Multiple sclerosis
Programmed cell death 1 receptor
Programmed cell death 1 ligand 1 protein
Programmed cell death 1 ligand 2 protein
Online Zugang:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/632
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