Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice

Abstract Background Phloretin is isolated from apple trees and could increase lipolysis in 3T3-L1 adipocytes. Previous studies have found that phloretin could prevent obesity in mice. In this study, we investigated whether phloretin ameliorates non-alcoholic fatty liver disease (NAFLD) in high-fat d...

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Bibliographic Details
Main Authors: Chian-Jiun Liou, Shu-Ju Wu, Szu-Chuan Shen, Li-Chen Chen, Ya-Ling Chen, Wen-Chung Huang
Format: Artigo
Language:Inglês
Published: BMC 2020-09-01
Series:Cell & Bioscience
Subjects:
HepG2
Lipogenesis
Lipolysis
Phloretin
non-alcoholic fatty liver disease
Online Access:http://link.springer.com/article/10.1186/s13578-020-00477-1
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