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Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives

Two new series of heterocyclic derivatives with potential anticancer activity, in which a pyrrolo[1,2-b]pyridazine or a pyrrolo[2,1-a]phthalazine moiety was introduced in place of the 3′-hydroxy-4′-methoxyphenyl ring of phenstatin have been synthesised and their structure-activity relationship (SAR)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lacramioara Popovici, Roxana-Maria Amarandi, Ionel I. Mangalagiu, Violeta Mangalagiu, Ramona Danac
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2019-01-01
Saila:Journal of Enzyme Inhibition and Medicinal Chemistry
Gaiak:
Sarrera elektronikoa:http://dx.doi.org/10.1080/14756366.2018.1550085
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