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Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives
Two new series of heterocyclic derivatives with potential anticancer activity, in which a pyrrolo[1,2-b]pyridazine or a pyrrolo[2,1-a]phthalazine moiety was introduced in place of the 3′-hydroxy-4′-methoxyphenyl ring of phenstatin have been synthesised and their structure-activity relationship (SAR)...
Gorde:
Egile Nagusiak: | , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Taylor & Francis Group
2019-01-01
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Saila: | Journal of Enzyme Inhibition and Medicinal Chemistry |
Gaiak: | |
Sarrera elektronikoa: | http://dx.doi.org/10.1080/14756366.2018.1550085 |
Etiketak: |
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