Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms

Summary: We compared three hospitalized patient cohorts and conducted mechanistic studies to determine if lipotoxicity worsens COVID-19. Cohort-1 (n = 30) compared COVID-19 patients dismissed home to those requiring intensive-care unit (ICU) transfer. Cohort-2 (n = 116) compared critically ill ICU p...

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Autores principales: Rodrigo Cartin-Ceba, Biswajit Khatua, Bara El-Kurdi, Shubham Trivedi, Sergiy Kostenko, Zaid Imam, Ryan Smith, Christine Snozek, Sarah Navina, Vijeta Sharma, Bryce McFayden, Filip Ionescu, Eugene Stolow, Sylvia Keiser, Aziz Tejani, Allison Harrington, Phillip Acosta, Saatchi Kuwelker, Juan Echavarria, Girish B. Nair, Adam Bataineh, Vijay P. Singh
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2022-05-01
Colección:iScience
Materias:
health sciences
virology
medical microbiology
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2589004222005934
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