Cholinergic Nerve Differentiation of Mesenchymal Stem Cells Derived from Long-Term Cryopreserved Human Dental Pulp In Vitro and Analysis of Their Motor Nerve Regeneration Potential In Vivo

The reduction of choline acetyltransferase, caused by the loss of cholinergic neurons, leads to the absence of acetylcholine (Ach), which is related to motor nerve degeneration. The aims of the present study were to evaluate the in vitro cholinergic nerve differentiation potential of mesenchymal ste...

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Main Authors: Soomi Jang, Young-Hoon Kang, Imran Ullah, Sharath Belame Shivakumar, Gyu-Jin Rho, Yeong-Cheol Cho, Iel-Yong Sung, Bong-Wook Park
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Assuntos:
dental pulp stem cells
tissue cryopreservation
cholinergic nerve differentiation
cell transplantation
Acceso en liña:http://www.mdpi.com/1422-0067/19/8/2434
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