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Towards discovery of inhibitors of the undecaprenyl-pyrophosphate phosphatase BacA by virtual high-throughput screening

Increasing resistance to common antibiotics is becoming a major challenge that requires the development of new antibacterial agents. Peptidoglycan is an essential heteropolymer of the bacterial envelope that ensures the integrity and shape of all bacteria and is also an important target for antibiot...

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Autores principales: Marko Jukič, Rodolphe Auger, Victor Folcher, Matic Proj, Hélène Barreteau, Stanislav Gobec, Thierry Touzé
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2022-01-01
Colección:Computational and Structural Biotechnology Journal
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2001037022001660
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