Epigenome-wide association of myocardial infarction with DNA methylation sites at loci related to cardiovascular disease

Abstract Background Development of cardiovascular disease (CVD), including coronary artery disease, arrhythmia, and ischemic stroke, depends on environmental and genetic factors. To investigate the epigenetic basis of myocardial infarction (MI), we performed an epigenome-wide association study for t...

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Hlavní autoři: Masahiro Nakatochi, Sahoko Ichihara, Ken Yamamoto, Keiko Naruse, Shigeki Yokota, Hiroyuki Asano, Tatsuaki Matsubara, Mitsuhiro Yokota
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2017-05-01
Edice:Clinical Epigenetics
Témata:
DNA methylation
Myocardial infarction
Epigenome-wide association study
Cardiovascular disease
Single nucleotide polymorphism
On-line přístup:http://link.springer.com/article/10.1186/s13148-017-0353-3
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