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Bevacizumab in metastatic breast cancer: when may it be used?
Tumor angiogenesis, which is necessary for breast cancer growth, invasion and metastases, is regulated by pro-angiogenic factors such as vascular endothelial growth factor (VEGF). Bevacizumab is a recombinant humanized monoclonal antibody that targets VEGF. The addition of bevacizumab to chemotherap...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
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SAGE Publishing
2011-03-01
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Schriftenreihe: | Therapeutic Advances in Medical Oncology |
Online Zugang: | https://doi.org/10.1177/1758834010397627 |
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