Ex vivo Platforms to Study the Primary and Recall Immune Responses to Intracellular Mycobacterial Pathogens and Peptide-Based Vaccines

Progress in the study of the immune response to pathogens and candidate vaccines has been impeded by limitations in the methods to study the functional activity of T-cell subsets proliferating in response to antigens processed and presented by antigen presenting cells (APC). As described in this rev...

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Bibliographic Details
Main Authors: William C. Davis, Asmaa H. Mahmoud, Gaber S. Abdellrazeq, Mahmoud M. Elnaggar, John L. Dahl, Victoria Hulubei, Lindsay M. Fry
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Veterinary Science
Subjects:
Mycobacterium tuberculosis
Mycobacterium bovis
Mycobacterium avium subspecies paratuberculosis
cellular immune response
intracellular pathogens
peptide vaccines
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.878347/full
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