3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection

Surgical implant-associated bone infections (osteomyelitis) have severe clinical and socioeconomic consequences. Treatment of chronic bone infections often involves antibiotics given systemically and locally to the affected site in poly (methyl methacrylate) (PMMA) bone cement. Given the high antibi...

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Bibliographic Details
Main Authors: JA Inzana, RP Trombetta, EM Schwarz, SL Kates, HA Awad
Format: Artigo
Language:Inglês
Published: AO Research Institute Davos 2015-11-01
Series:European Cells & Materials
Subjects:
Bone
Staphylococcus aureus
osteomyelitis
three dimensional printing
calcium phosphate
ceramics
antibiotics
drug delivery
Vancomycin
Rifampin.
Online Access:http://www.ecmjournal.org/papers/vol030/pdf/v030a16.pdf
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