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Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity.

Calcineurin inhibitors are powerful immunosuppressants that revolutionized organ transplantation. However, non-immune effects of the calcineurin inhibitor, such as cyclosporine A (CsA), have significantly hindered their use. Specifically, nephrotoxicity, which is associated with tubulointerstitial f...

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Auteurs principaux: Jennifer L Gooch, Clayton King, Cynthia E Francis, Paul S Garcia, Yun Bai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2017-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC5393575?pdf=render
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