HNF4α and CDX2 Regulate Intestinal <i>YAP1</i> Promoter Activity

The Hippo pathway is important for tissue homeostasis, regulation of organ size and growth in most tissues. The co-transcription factor yes-associated protein 1 (YAP1) serves as a main downstream effector of the Hippo pathway and its dysregulation increases cancer development and blocks colonic tiss...

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Auteurs principaux: Sylvester Larsen, Johanne Davidsen, Katja Dahlgaard, Ole B. Pedersen, Jesper T. Troelsen
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2019-06-01
Collection:International Journal of Molecular Sciences
Sujets:
Hippo pathway
intestinal epithelium
yes-associated protein 1 (YAP1)
transcriptional regulation
gene regulation
transcription factor
cellular regulation
Accès en ligne:https://www.mdpi.com/1422-0067/20/12/2981
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