FasL and TRAIL signalling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control.

Cutaneous leishmaniasis (CL) is associated with chronic inflammation and ulceration of the skin. Tissue macrophages serve as host cells and immune activation is necessary for parasite clearance. The balance between immune-mediated tissue destruction and successful clearance of infection is delicate....

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Bibliographic Details
Main Authors: Bence eRethi, Liv eEidsmo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
Keratinocytes
Macrophages
Neutrophils
cutaneous leishmaniasis
FasL
TRAIL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00163/full
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