With Great Age Comes Great Metastatic Ability: Ovarian Cancer and the Appeal of the Aging Peritoneal Microenvironment

Age is one of the biggest risk factors for ovarian cancer. Older women have higher rates of diagnosis and death associated with the disease. In mouse models, it was shown that aged mice had greater tumor burden than their younger counterparts when intraperitoneally injected with ovarian tumor cells....

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Autors principals: Elizabeth I. Harper, Emma F. Sheedy, M. Sharon Stack
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2018-07-01
Col·lecció:Cancers
Matèries:
ovarian cancer
age
tumor microenvironment
extracellular matrix
mesothelial cells
immune
fibroblast
adipocytes
peritoneum
Accés en línia:http://www.mdpi.com/2072-6694/10/7/230
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