Secondary Unconjugated Bile Acids Induce Hepatic Stellate Cell Activation

Hepatic stellate cells (HSCs) are key players in liver fibrosis, cellular senescence, and hepatic carcinogenesis. Bile acids (BAs) are involved in the activation of HSCs, but the detailed mechanism of this process remains unclear. We conducted a comprehensive DNA microarray study of the human HSC li...

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Main Authors: Kunihiro Saga, Yukio Iwashita, Shinya Hidano, Yuiko Aso, Kenji Isaka, Yasutoshi Kido, Kazuhiro Tada, Hiroomi Takayama, Takashi Masuda, Teijiro Hirashita, Yuichi Endo, Masayuki Ohta, Takashi Kobayashi, Masafumi Inomata
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Assuntos:
hepatic stellate cell
secondary unconjugated bile acid
DNA microarray
tumor necrosis factor signaling pathway
Acceso en liña:http://www.mdpi.com/1422-0067/19/10/3043
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