Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer

Colorectal cancer (CRC) is one of the most common and recurrent types of cancer, with high mortality rates. Several clinical trials and meta-analyses have determined that the use of pharmacological inhibitors of cyclooxygenase 2 (COX-2), the enzyme that catalyses the rate-limiting step in the synthe...

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Main Authors: Alicia M. Hidalgo-Estévez, Konstantinos Stamatakis, Marta Jiménez-Martínez, Ricardo López-Pérez, Manuel Fresno
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Assuntos:
cyclooxygenase
prostaglandin
Colon cancer
therapy
tumor development
metastasis
Acceso en liña:https://www.frontiersin.org/article/10.3389/fphar.2020.00533/full
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