Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer

Colorectal cancer (CRC) is one of the most common and recurrent types of cancer, with high mortality rates. Several clinical trials and meta-analyses have determined that the use of pharmacological inhibitors of cyclooxygenase 2 (COX-2), the enzyme that catalyses the rate-limiting step in the synthe...

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Bibliographische Detailangaben
Hauptverfasser: Alicia M. Hidalgo-Estévez, Konstantinos Stamatakis, Marta Jiménez-Martínez, Ricardo López-Pérez, Manuel Fresno
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-04-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
cyclooxygenase
prostaglandin
Colon cancer
therapy
tumor development
metastasis
Online Zugang:https://www.frontiersin.org/article/10.3389/fphar.2020.00533/full
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