Circular RNA ADAM9 facilitates the malignant behaviours of pancreatic cancer by sponging miR-217 and upregulating PRSS3 expression

Pancreatic cancer (PC) is a highly lethal human cancer. We previously found that Serine protease 3 (PRSS3), as an oncogene, is significantly upregulated in PC. In this study, we aimed to investigate the potential mechanism of PRSS3 dysregulation in PC. In this research, low miR-217 and high circ-ADA...

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Hlavní autoři: Chenju Xing, Hua Ye, Weiwei Wang, Miaomiao Sun, Jianying Zhang, Zhihua Zhao, Guozhong Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2019-12-01
Edice:Artificial Cells, Nanomedicine, and Biotechnology
Témata:
Pancreatic cancer
circular RNA
microRNA
ceRNA
ERK signalling
prognosis
On-line přístup:https://www.tandfonline.com/doi/10.1080/21691401.2019.1671856
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