Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood

Abstract Background Genetics explains a small proportion of variance in body mass index at the population level. Epigenetics, commonly measured by gene methylation, holds promise for understanding obesity risk factors and mechanisms. Methods Participants were 431 adolescents aged 10–15 years. BMI z-...

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Autores principales: Jocelyn Dunstan, Joseph P. Bressler, Timothy H. Moran, Jonathan S. Pollak, Annemarie G. Hirsch, Lisa Bailey-Davis, Thomas A. Glass, Brian S. Schwartz
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2017-03-01
Colección:Clinical Epigenetics
Materias:
Obesity
Epigenetics
DNA methylation
Sex differences
LEP
CRH
Acceso en línea:http://link.springer.com/article/10.1186/s13148-017-0327-5
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